ImmuneDB is a database-backed system to analyze and store large amounts (terabytes) of high-throughput B-cell receptor (BCR) and T-cell receptor (TCR) data. Although it can be used as a stand-alone package for comprehensive repertoire profiling, ImmuneDB excels at acting as a central data store and interface between other tools such as IgBLAST, the Immcantation Framework, MiXCR, and VDJtools via AIRR compliant importing and exporting routines.

Feature Highlights

  • Relational storage of repertoire data: Sequences, annotations, clones, lineages, and statistics are all stored in a relational database to promote consistent formatting and easy querying.

  • Consolidated metadata: Custom study, experiment, and replicate metadata is stored alongside your sequencing data in a non-redundant format to avoid inconsistencies and errors over the life of your study.

  • Web interface: ImmuneDB provides a built-in web interface for interactive exploration of data.

  • Interoperability: With AIRR compliant input and output methods, ImmuneDB can interface with other software in the AIRR ecosystem. Other output formats include Change-O and VDJtools.

  • Proven reliability: ImmuneDB is used by multiple labs to manage terabytes of data comprised of billions of sequences in dozens of projects.

Quick Start

To get started immediately, please see the Docker installation instructions.